The CALVIH Study: How to Handle Renal Stones in Persons Living with HIV<sub>1</sub>?

Background: Renal stone (RS) is a highly prevalent disease in our societies and mostly secondary to lifestyle habits. HIV1 patients often experience RS, although specific risk factors are not known. Despite other priorities, comprehensive work-up should be offered avoid recurrences (50% 5 years). Purpose Methods: The aim of the study describe how handle RS persons living with suggest understanding mechanisms involved composition helps customize therapy prevent recurrences. We prospectively performed complete cohort 23 referred highly-specialized center by HIV physicians. Results: Inclusion was colic episode spontaneous elimination (74%), bilateral (67%), obstructive (67%); 53% underwent urologic interventions. Mean age 34 ± 16 years old BMI 22.5 3 (one-third metabolic syndrome). History showed only one (22%), >one (74%) or >4 (4%). Estimated GFR 78 24 ml/min/1.73m2 (mean Cr 101 μmol/L), were classified CKD stage 3. Stone analysis available for 7 6/7 patients, calcium metabolism fully explored (2 absorptive hypercalciuria, 4 renal primitive hypercalciuria). Retained mechanism uric acid dependent one, oxalic three three. Very few exposed known environmental were/had been darunavir atazanavir, 1 efavirenz, acetazolamide, 2 allopurinol. Conclusion: related ARV. Understanding critical offering dietetic counselling therapy. role physicians important due high prevalence context disease.